Blog
Proteomics in Practice
The research behind our work, plain-language explainers on proteomics and LC-MS, and news from Trace Labs.
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What Blood Proteins Reveal About ME/CFS
A proteomics study of plasma from people with ME/CFS points to changes in clotting, the immune system and the lining of blood vessels.
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Why Your Wine Isn’t Cloudy: The Proteins Behind a Clear Glass
The grape proteins that can turn white wine hazy, how winemakers remove them, and how LC-MS helps them do it more precisely.
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Design Before You Digest: 5 Questions to Answer Before You Send Samples
Most proteomics studies that disappoint fail at the design stage. Five questions to answer before your samples reach the lab.
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What Is Trapped Inside Long COVID Microclots?
We looked inside the microclots of 99 people with long COVID and found clotting proteins, inflammatory molecules and antibodies caught in the mesh.
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Your DNA Isn’t the Whole Story
Genes are the recipe book. Proteins are what is actually cooking. Why studying proteins tells us things DNA cannot.
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Same Symptoms, Different Chemistry: Telling POTS and Long COVID Apart
Chemical changes to proteins inside microclots appear to distinguish POTS, long COVID and long COVID with POTS, even when protein levels barely differ.
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Healing Diabetic Wounds: Four Studies, One Question
Four studies with Dr Mari van de Vyver’s group, from the first days after injury to cell therapies, all asking why diabetic wounds fail to heal.
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Testing a Traditional Remedy Against TB
South Africa has one of the world’s highest TB burdens. How proteomics supports TB research, and what a lab study of Pelargonium sidoides found.
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A Gene Variant, Parkinson’s Disease and the Synapse
What happens to the proteins in brain-like cells when a Parkinson’s-linked variant in the NRXN2 gene is switched on.
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When the Medicine Crosses Over: What a New Study in Zebrafish Tells Us About Antidepressants and Pregnancy
What a zebrafish study reveals about desmethylsertraline, the main metabolite of sertraline, and antidepressant use during pregnancy.
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From the Cord to the Clinic: What My Newborn Reminded Me About Wound Healing
A 2am reflection on a study using umbilical cord blood serum and amniotic membrane to heal diabetic wounds.
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Turning Science into Solutions: How Trace Labs Is Expanding Proteomics Capability at Stellenbosch University
A new Expert Research Fellow affiliation brings Trace Labs' proteomics and protein chemistry expertise to Stellenbosch University.
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The Ticking Clock: Why 3D Cell Cultures Are a Moving Target
HepG2 liver spheroids keep changing over 28 days in culture, and that matters for anyone using them to screen drugs.
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SARS-CoV-2 Spike Protein S1 and Its Role in Hypercoagulation: A Study on Fibrin(ogen) Resistance to Fibrinolysis
How the spike protein S1 makes clotting proteins resist breakdown, and what that may mean for microclots in COVID-19 and long COVID.
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Unpacking Long COVID: How Proteomics Is Leading the Charge
How proteomics is helping researchers understand what happens in the body in long COVID.
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The Essential Role of Proteomics Analysis in Academic Research
Why proteomics analysis has become an essential tool for academic researchers.
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How LCMS and Proteomics Work Hand in Hand
How liquid chromatography-mass spectrometry makes large-scale protein analysis possible.
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What Is LCMS?
An introduction to liquid chromatography-mass spectrometry and how it works.
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The Trio of Discovery: How Biochemistry, Proteomics and LCMS Work Together
How biochemistry, proteomics and LC-MS combine to drive discovery.
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The Impact of Proteomics Across Industries
How proteomics is used beyond the research lab, from food and agriculture to medicine.
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The One Where We Discovered That Increased Antiplasmin in Long COVID Contributes to Microclots
How raised antiplasmin levels in long COVID contribute to microclots that resist breakdown.
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What Is Proteomics?
An introduction to proteomics, the large-scale study of proteins.
Have Research Like This in Mind?
Many of these studies started with a conversation about samples and a research question. We'd be glad to hear about yours.